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These combined effects make DSIP a promising candidate for therapeutic interventions aimed at treating major depression, especially when linked to stress and sleep disruptions

S7 10 ), integrative cryo-EM and AlphaFold 3D reconstruction (Fig

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To date, there are no large-scale, randomised controlled trials (RCTs) the gold standard of clinical evidence that have conclusively demonstrated its efficacy for hair regrowth in humans

The main therapeutic benefit of these approaches comes from lowering the overall urate burden rather than from direct anti-inflammatory effects