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Chronic inflammation is often diagnosed alongside other medical conditions, such as cardiovascular disease, diabetes, and autoimmune disorders, which can significantly impact morbidity and mortality

It's a condition where conventional treatments, like pain medication or cortisone shots, often feel like a temporary patch on a much deeper problem

Chronic overactivation of HIF1, increased cytoplasmic and mitochondrial calcium overload, and other dysregulations of mitophagy exacerbate ischemia-reperfusion injury