We also observed upregulation of mesenchymal markers ( VIM and TWIST ) and downregulation of epithelial markers ( CDH1 , CLDN7 and TJP3 , Figures 2F, G ) , consistent with earlier observations in other persister cell models ( Figure 2 CRC Persister Cells Are Vulnerable to Ferroptosis To effectively eliminate CRC DTP cells, we sought to identify therapeutic vulnerabilities in persister cells that are absent in parental and regrown cells
By tissue type, the application that has the strongest evidence base is soft tissue: muscle strains, ligament sprains, and chronic tendinopathies
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