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Zhao X, Wu P, Yang Z, Miao RR (2024) Relationship between the efficacy and adverse effects of methotrexate and gene polymorphism

H 2 O 2 induces nuclear transport of the receptor tyrosine kinase c-MET in breast cancer cells via a membrane-bound retrograde trafficking mechanism

The most frequent issues reported from the phase 3 studies are nausea (19%), fatigue (6%), skin darkening (4%), dizziness (4%), and the development of moles (4%)

It classifies the compound as Category 2 indicating significant safety concerns when used in compounding

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