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O-GlcNAcylation: a novel therapeutic target for brain disorders As discussed above, O-GlcNAcylation is implicated in various CNS disorders, including neurodevelopmental disorders, neurodegenerative diseases, psychiatric diseases, and CNS injuries

Research has revealed that the complex modulates the expression of over 4,000 mammalian genes, with particularly pronounced effects on genes involved in tissue repair, antioxidant defense, and inflammatory resolution

PLoS ONE 7(1):e29830 Shamsuddin N, Blair J, Kumar A (2011) Toll like receptor 2 mediates the innate immune response of retinal Muller glia to Staphylococcus aureus

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