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Abstract Significance: The antiulcer peptide, stable gastric pentadecapeptide BPC 157 (previously employed in ulcerative colitis and multiple sclerosis trials, no reported toxicity (LD1 not achieved)), is reviewed, focusing on the particular skin wound therapy, incisional/excisional wound, deep burns, diabetic ulcers, and alkali burns, which may be generalized to the other tissues healing

Studies have explored its potential in models of ulceration, inflammatory bowel disease analogues, and intestinal fistulas

A: Both compounds have demonstrated angiogenic and pro-healing effects in preclinical models, but through mechanistically distinct pathways