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Patients should be informed that gastrointestinal symptoms are dose dependent, common during treatment initiation and escalation, usually transient, influenced by the starting dose, and speed of titration ( Adjunctive dietary and behavioral measures may aid during treatment initiation and dose escalation

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Musculoskeletal Problems Accutane patients may experience muscle cramps, joint pain and bone pain

doi: 10.4274/jtgga.2018.0077 60 JensterleMPirBGoriarKDolanVJaneA

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