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Although for some genes it has been suggested that methylation occurs in an all-or-none manner ( Reference Belshaw, Elliott and Williams 67 ) , it is also apparent that particular cytosines within a CpG island can have a distinctly greater likelihood of being methylated ( Reference Mund, Beier and Bewerunge 68 , Reference Feltus, Lee and Costello 69 ) than others

[ Links ] Liu WM, Fowler DW, Dalgleish AG (2010) Cannabis-derived substances in cancer therapyan emerging anti-inflammatory role for the cannabinoids

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2024), along with the common approach of converting biomarker results to exposure estimates for a risk assessment (see Sect