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In addition, the negative NMO and MOG antibody tests effectively rule out neuromyelitis optica and MOG-associated disorders as alternative causes, leaving the possibility of clinically isolated syndrome (CIS) or an early demyelinating condition, such as multiple sclerosis (MS), as more probable explanations

Remember that while B12 injections can be beneficial for those with deficiencies or certain health conditions, they're not suitable for everyone

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Computed tomography myelography is recommended if MRI cannot be performed (e.g., the patient has spinal or cardiac instrumentation or other hardware that may not be MRI compliant)

Injection volumes stay small (0.05-0.1 mL), which community sources describe as more comfortable for subcutaneous delivery