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GHK-Cu acts through three main pathways: epigenetic modulation (4,000+ genes, 31.2% of the genome), stimulation of collagen/elastin/GAG synthesis, and copper transport for the activation of antioxidant SOD and wound-healing enzymes

Lien and Fuchs, 2014)

1C), whereas APAP fed adults show increased APAP immunoreactivity, particularly in the abdomen (Fig

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Together, these findings unveil ACase as a novel regulator of the ferroptosis pathway and open promising therapeutic avenues for targeting senescence-linked disorders and advancing healthy aging strategies.