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Whilst B12 injections have a clear therapeutic role in treating deficiency states, lipotropic injections remain controversial within evidence-based medicine, with limited peer-reviewed research supporting their efficacy for weight management or metabolic enhancement

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However, these conditions are rare 9

According to The National Sunflower Association, there is evidence that both the plant and its oil were used by American Indians in the area of Arizona and New Mexico about 3000 BC

Vennerstrom JL, Makler MT, Angerhofer CK, Williams JA (1995) Antimalarial dyes revisited: Xanthenes, azines, oxazines and thiazines