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In the retina, GPER activation can promote the survival of retinal neurons and enhance the function of photoreceptors, which is crucial for maintaining a normal visual capacity [114]

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The needle depth determines how deep the microchannels reach and therefore how deeply the subsequent topical application can penetrate

PCO 2 : Partial pressure of carbon dioxide

Its primary functions include: Detoxification: Glutathione helps detoxify harmful substances in the liver, neutralizing free radicals and heavy metals