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Western blot analysis further showed that cartilage generated from FOXO4-DRI pre-treated chondrocytes displayed higher protein levels of p16, p21, and p53 (Figure 3B)

Furthermore, the KEGG results revealed associations of these DEGs with pathways related to cholesterol metabolism, amino acid biosynthesis, and primary bile acid biosynthesis, among others (Figure 7D)

It increased survival of cultured enteric neurons and proliferation of enteric glial cells, suggesting direct neuroprotective effects on the enteric nervous system that could influence central serotonin tone through vagal signaling

Minimally invasive, with natural-looking results and high density

Injected into the affected area or muscle for faster absorption