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Through a series of enzyme-driven reactions, Phase 1 alters the structure of toxins via: Oxidation introducing oxygen to increase chemical reactivity Reduction removing oxygen to alter molecular configuration Hydrolysis breaking chemical bonds using water Hydration adding water molecules to facilitate further processing Dehalogenation removing halogen atoms such as chlorine or bromine The purpose of Phase 1 is not elimination, but activation

Wash the plate five times

This could be due to the thioredoxin property of GSH due which it controls the different enzymes of photosynthesis

Zubkova EV, Robaire B (2004) Effect of glutathione depletion on antioxidant enzymes in the epididymis, seminal vesicles, and liver and on spermatozoa motility in the aging brown Norway rat

(December 1980)