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Threonine 15 and 365 are important for UGT74F2 and UGT74F1 specificity, respectively Within the SA binding site, all residues are identical between UGT74F1 and UGT74F2 with the exception of position 15, which is a serine in UGT74F1 but threonine in UGT74F2 (Supplementary Fig

Because of the pathways it activates, there is some concern that it may drive the growth of existing cancer cells

Congenital hypothyroidism: A 20202021 consensus guidelines update-an ENDO-European reference network initiative endorsed by the European society for pediatric endocrinology and the european society for endocrinology

See section 4

Oxidative stress determination is limited in daily clinical practice, primarily due to the difficulty in measuring the different aspects of oxidative stress, which entails several tests: oxidized glutathione, reduced glutathione, glutathione peroxidase, and glutathione reductase (GRd)