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As evidence has shown that IL-17 can increase depression and depression-like behaviors through the activation of microglia and inducing neuronal death, we can speculate that increased Th17 cells and IL-17A, induced by gut dysbiosis during the onset of GD are involved in the immune response of depression, exacerbating depressive symptoms

D.NiitsuY.TakayamaT.et al (1998)

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