It's not dangerous, but it can: Add 13kg of scale weight (masking actual fat loss) Cause visible puffiness in legs or hands Be uncomfortable if severe What to do if you notice edema: Reduce KLOW dose by 50% and reassess after 2 weeks If on a daily frequency, drop to 3x/week If it persists, switch to pinning BPC-157 and GHK-Cu separately, leaving TB-500 out until the edema resolves Stay well-hydrated (counterintuitively, more water can help flush the retained fluid) Most people find edema resolves once the body adapts in weeks 24, or by reducing frequency
There are options ranging from pure ascorbic acid to water-soluble or oil-soluble Vitamin C derivatives
Additional to this pathway, there are other pathways that involve different adaptor proteins, but ultimately lead to the activation of NF- and other inflammatory signaling molecules, such as AP-1 (Yamamoto et al., 2002
Introduction# Epitalon and NAD+ represent two of the most discussed approaches to biological aging, targeting fundamentally different cellular mechanisms
Oxidative stress plays a role in the progression of type 2 diabetes