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4.2 Iron overload and dysregulated metabolism Iron overload is a critical factor that drives ferroptosis and worsens ARDS pathology

While the 28-day treatment period and use of only male rats were consistent with standard protocols to reduce variability in early-phase toxicological studies, these choices limit the extrapolation of our findings to chronic exposure scenarios and across sexes

The cells also were assayed for the cytotoxicity effects of menadione using the CellTox Green Cytotoxicity Assay

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Oocyte mitophagy is critical for extended reproductive longevity