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The mechanism involves PRPs growth factorsparticularly PDGF, VEGF, and IGF-1stimulating the proliferation of dermal papilla cells, improving scalp vascularity, prolonging the anagen (growth) phase of the hair cycle, and reducing the inflammation that drives follicular miniaturization in androgenetic alopecia

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When the gut environment is calm, vagal tone improves, shifting the autonomic nervous system away from the hyper-aroused "fight or flight" sympathetic state and toward the restorative "rest and digest" parasympathetic state