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Extracellular nucleosomes and NET-bound histones provide negatively charged surfaces that can activate the contact pathway via factor XII (FXII) autoactivation, while NET-associated tissue factor (TF) and TF-bearing microparticles amplify extrinsic pathway signaling in certain inflammatory contexts [64]

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To assess the rats immediately following post-operative recovery and to ensure the consistency of injury based on this expected deficit in motor function, the initial application of the regimen that was used in drinking water, BPC 157

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