A 2025 matched-cohort study found men who started testosterone therapy had significantly higher rates of tendon tears and repairs at one and two years compared to controls, a pattern the authors attributed to testosterone's effect on tendon biomechanics outpacing the tissue's regenerative capacity Sherman et al
It is important to consider potential variations in efficacy among subjects and potential differences in potency compared to injectable formulations
138 Pyroptosis is implicated in infections, autoimmune disorders, and metabolic diseases, including MASLD
Clinical studies indicate that NPS prevalence and severity vary across different AD stages and types
For instance, the development of autoimmune diseases is stimulated by iodine (excess or deficiency), smoking, stress, and chemical contaminants (like polyaromatic hydrocarbons), medicine (like amiodarone and interferon-alpha (IFN), and bacterial and viral infections (like hepatitis C virus and Yersinia enterocolitica)
