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A 2012 analysis by Pickart and Margolina identified that GHK-Cu modulates the expression of over 4,000 human genes approximately one-third of all genes with a known biological function

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Taken together, as there are no guidelines available for the tapering or discontinuation of current treatments of inflammatory diseases, we suggest that tapering DMARDs should, for one, be based on shared decision making with the patient being allowed to find individual ways of reducing the drug burden, as is currently shown for RA patients