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Tretinoin is one of the most widely prescribed topical retinoids for concerns like acne, fine lines, wrinkles, uneven texture, and dark spots because it helps increase skin cell turnover and stimulate collagen production over time

It is reported that RE acutely augments the activity of the aromatase enzyme which results in an increase in the biosynthesis of estrogen from androgens (Nelson and Bulun, 2001

It accelerates tendon fibroblast outgrowth, increases cell survival under stress, and promotes cell migration, likely through the activation of the FAK-paxillin pathway

And this one does all three in terms of area covered and wavelength

[Abstract]2024 Feb 2;10(5):eadj7813