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Medication side effects were the major reason for withdrawal from the studies
Cost-efficiency: Long-term, at-home injections can be more budget friendly than repeat clinic visits
Group-III: HFD and nicotine (1.5 mg/kg, b.wt, I.P) (Sinha-Hikim AP, et al ., 2017)+Vitamin-U (100 mg/kg, b.wt) (Sokmen BB, et al ., 2012)
Regeneration of Non-Enzymatic Antioxidants GSH not only neutralizes reactive species directly, but also helps regenerate oxidized antioxidants, including vitamin C and polyphenols (quercetin, resveratrol), enhancing overall ROS-scavenging capacity (9, 16-17)
Preclinical studies have revealed that specific mGluR subtypes mediate significant neuroprotective effects that reduce toxin-induced midbrain dopaminergic neuronal death in animal models of Parkinsons disease [41]
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