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doi:10.3389/fcell.2022.800925

demonstrated that the luminal androgen receptor (LAR) subtype of TNBC is characterized by the upregulation of glutathione metabolism, which allowed the utilization of Glutathione peroxidase 4 (GPX4) inhibitors to induce ferroptosis of TNBC [15]

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Vaccines based on tumor-specific antigens are promising new therapeutic strategies, neoantigens can be presented to T cells by DCs system as a pool of short (8 to 11 amino acids) or long (15 or more residues) individual synthetic peptides or as unique long single molecule that concatenates the different neoantigens spaced by linker sequences (prepared as DNA, RNA or soluble protein)

The number of cells in five of the central 25 squares was counted and multiplied by 100,000 to obtain number of cells per ml of media