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This change in sulfide bond formation then causes protein misfolding.[ref] Mitochondrial dysfunction: Elevated homocysteine levels have been shown to cause mitochondrial dysfunction

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Tabernero J, Grothey A, Van Cutsem E, Yaeger R, Wasan H, Yoshino T, Desai J, Ciardiello F, Loupakis F, Hong YS, Steeghs N, Guren TK, Arkenau HT, Garcia-Alfonso P, Elez E, Gollerkeri A, Maharry K, Christy-Bittel J, Kopetz S

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A therapeutic misadventure

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Among the members of the caspase family, caspase-3 is a crucial modulator of apoptosis in mammalian cells [42]

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