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While certain studies have reported increased SARS-CoV-2-specific T cell responses in LC in comparison to non-LC cases [184,221], a rapid decay of subsets of SARS-CoV-2-specific CD8 + T cells was observed in the context of LC in another study [187]

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This sensitization leads to an augmented secretion of cytokines linked to Th1 and Th17 responses when exposed to pro-inflammatory agents ( Distinct subsets of T cells exhibit variable dependency on the biosynthesis of fatty acids, a process particularly crucial for the development of Th17 cells ( A diet rich in fats stimulates the formation of Th17 cells and enhances the activity of key enzymes in lipid metabolism, such as ACC1 ( 3.1.1 Polyunsaturated fatty acid Polyunsaturated fatty acids (PUFAs) are a beneficial class of lipids crucial for maintaining optimal human health

[21] [22] This condition impairs B12 absorption in the terminal ileum and typically requires lifelong parenteral replacement therapy

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