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There is evidence that ACh induces a range of effects on immune cells

doi: 10.1126/science.aan4665 167 TastanBAriozBITufekciKUTarakciogluEGonulCPGencKet al

Unlike traditional tumor vaccines, IGV-001 is prepared by mixing tumor tissue removed from the patients brain with an insulin-like growth factor 1 receptor antisense oligonucleotide (IMV-001), which inhibits tumor growth

DErcole AJ, Stiles AD, Underwood LE