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Mainly, it blocks adenosine receptors that allow endogenous adenosine to regulate a wide range of physiological processes (Ferre et al., 2018)

Serum levels of TCDD and dioxin-like chemicals in Rhesus monkeys chronically exposed to dioxin: correlation of increased serum PCB levels with endometriosis

In the chronic toxicity experiment, L-NAME caused severe tissue damage (myocardial and hepatic cell necrosis, necrosis of the lymphoid cells in the spleen) while L-arginine provoked predominantly congestion, edema and hemorrhages in all organs

[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Aoyama K

Clin Dermatol 2012;30:345-8