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In some instances, the formulations described herein provide a deliverable osmolarity (e.g., at a target site (e.g., perilymph) that causes minimal disturbance to the environment of the inner ear and causes minimum discomfort (e.g., vertigo and/or nausea) to a mammal upon administration

When free radicals overwhelm the bodys antioxidant defenses, inflammation rises, and metabolic function declines

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deliver nutrients and botanicals that support thyroid hormone production, conversion, and overall hormone balance