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This includes: Binders should be titrated slowly and paired with hydration and regular elimination to minimize Herxheimer reactions

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We know for every drug thats been approved going through the safety profile, the toxicology, the pharmokinetics that has then been approved in humans, theres just as many, if not more, that have fallen by the wayside along the way because they dont have a specific benefit for whatever it was we were looking to treat, he said