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[1] [7] Tirzepatide should not be used during pregnancy or breastfeeding, and women of reproductive potential should use effective contraception
Cause of Low B12 levels Pernicious anaemia vegan diet malabsorption syndromes coeliac sprue Crohn's ulcerative colitis (UC) "food-bound cobalamin malabsorption syndrome" predisposing factors include atrophic gastritis, long term proton pump inhibitor or H2 antagnoist use, chronic alcoholism, gastrectomy/gastric bypass surgery, pancreatic exocrine failure, AIDS myeloma (paraprotein related assay interference) pregnancy combined oral contraceptive pill/HRT pancreatric insufficiency metformin, acute phase situations
Community-reported research protocols cite 812 week cycles, though those are not clinical recommendations
Progressive improvement in comfort and function
The amino acid sequence (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) includes an unusual triple proline structure conferring exceptional stability
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