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In asthma patients, a correlation has been found between the degree of bronchial responsiveness to methacholine and the production of superoxide anion by peripheral polymorphonuclear leukocytes (28,29)

+ Preclinical work examines its role in cellular repair processes , metabolic efficiency, and stress-response signaling

Solanum nigrum with dynamic therapeutic role: a review

For example, deletion of the genes encoding BACH1 [65] and JMJD3 [66], negative regulators of Nrf2, upregulated the expression of Nrf2, inhibiting the LPS-induced inflammatory response and ferroptosis, and ameliorating LPS-induced ALI