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Preclinical studies demonstrate that DSIP can alter pain threshold responses, with observed effects that are not reversed by opioid receptor antagonists such as naloxone, suggesting involvement of non-opioid or indirect neuromodulatory pathways [7]

The kidneys are highly dependent on glutathione to maintain optimum function

10.1038/cdd.2009.107 Cell Death Differ

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Lengthy treatment protocols, an inability to afford expensive interventions (especially assisted reproductive techniques), and financial difficulties incurred through treatment can add to the burden of stress