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Additionally, Oga heterozygous ( Oga +/ ) mice, which exhibit chronically elevated levels of O-GlcNAcylation, display antidepressant-like behaviors, and altered synaptic transmission in the medial prefrontal cortex (mPFC) [46]

Single-use protocols can use sterile water, but the peptide must be used within 72 hours and stored at 28C

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4 Discussion The results of these two studies found no clinically relevant differences in cagrilintide pharmacokinetics in people with renal or hepatic impairment, regardless of severity