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Mechanical ventilation is essential in patients with respiratory failure who show resistance to oxygen therapy, and hemodynamic support is essential for the management of patients with septic shock [,,,]

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At the individual level, exposure to microplastics through uptake (e.g., ingestion and inhalation) or skin contact can cause serious health damage, including inflammation and oxidative stress in humans and animals 8,9

ROS levels in these cells were assessed using DCFH-DA staining followed by fluorescence microscopy, revealing that BV2-metformin-loaded PLGA reduced intracellular ROS compared to uncoated nanoparticles and restored mitochondrial membrane potential (MMP) via JC-1 staining