As much of the MRS evidence in schizophrenia relates to the ACC, this was our primary region of interest
If DSIP enhances deep sleep, it could theoretically amplify this natural hormone release window
the internal chronic inflammatory cells, particularly tgams, continue to release inflammatory mediators and proteases such as interleukin-1 (IL-1 ), tumor necrosis factor - (TNF - ), and matrix metalloproteinases (MMPs)
The primary antibodies employed were: P53 (Proteintech, 60283-2-Ig), pSer46-P53 (CST, 2521), FOXO4 (Proteintech, 21535-1-AP), P21 (CST, 2947), P16 (CST, 18769), BAX (CST, 2772), BCL2 (CST, 3498), Ki-67 (Proteintech, 84192-4-RR), Lamin B (CST, 13435), Cleaved Caspase 3 (CST, 9664), -H2AX (Abcam, ab81299), and GAPDH (Abcam, ab8245) as an internal reference for normalizing protein expression levels
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