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MRI examinations have uncovered microbleeds in the deep layers of the motor cortex in ALS patients, while the precise mechanisms driving this BBB impairment in ALS remain elusive [243]

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The inhibitory effects of HDAC1 and HDAC10 expressions were also observed in the zebrafish epilepsy model triggered by a GABA A R 2 subunit (GABRG2) mutation after treatment with SAHA [151]

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