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The peptide enhances Wnt/-catenin signaling, a critical pathway for hair follicle development and regeneration, while simultaneously suppressing TGF- signaling in the follicle bulge region where stem cells reside

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Cytosolic mtDNA then acts as a persistent trigger of innate immune pathways (e.g., cGAS-STING, NLRP3), fueling chronic inflammation that drives accelerated aging and non-AIDS comorbidities despite virological suppression

Maedler, K., Oberholzer, J., Bucher, P., Spinas, G