Excessive iron accumulation, coupled with its propensity to generate reactive oxygen species (ROS), suggests its potential involvement in various chronic illnesses, including diabetes, neurological disorders, cardiomyopathy, and several human cancers, such as lung cancer, colorectal cancer, and breast cancer (Jiang et al., 2004
Studies have shown that in severe cases, this deficiency exacerbates endothelial dysfunction, contributing to vascular problems like poor circulation or heightened risk of heart issues
doi: 10.1021/acs.jafc.1c01382 58 XuT
Fortunately, in response to regular exercise training, resting levels of glutathione increase as an adaptation by the body to effectively deal with the increase in free radicals that commonly results secondary to the exercise training
This transformation engenders heightened accessibility and potency of antioxidants, thereby fostering equilibrium in adrenal hormone levels and mitigating the impact of oxidative stress (180)