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Curcumin mitigated the neurotoxic effects induced by glutamate through the inhibition of endoplasmic reticulum stress-associated activation of TXNIP/NLRP3 inflammasome in a manner that relied on 5 AMP-activated protein kinase, as documented in reference ( In an experimental study, a pretreatment approach was employed to assess lovastatins potential as a neuroprotective agent in the context of a subsequent moderate TBI (CCI-induced TBI), as described in reference (S.-F

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