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For example, someone with cardiovascular symptoms wouldnt meet the criteria unless they also had gastrointestinal or dermatological symptoms.[ref] One form of MCAS, now called idiopathic anaphylaxis , involves sudden, often random-seeming episodes of throat swelling, itching, wheezing, shortness of breath, stomach pain, nausea, vomiting, diarrhea, and a drop in blood pressure

Exclusion criteria were: (a) in-vitro RCTs

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The restoration of biomechanical properties demonstrated in animal ligament models suggests potential for improved outcomes compared to rest and splinting alone