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In osteoarthritis (OA), SHMT2 expression is elevated in chondrocytes, and miR-370 affects the pathological process of osteoarthritis by altering 1C metabolism and DNA methylation through negative regulation of SHMT2 expression [150]

[DOI] [PMC free article] [PubMed] [Google Scholar] 151.Liu C., Liang M.C., Soong T.W