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Specifically, it has been shown that 100 mg LA/kg body weight/day for 2 weeks i.p

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Free radicals are molecules that are potentially toxic to cells

This happened when totally inconsistent results were published by several groups using JNK2-deficient mice [36, 134136] and it was later discovered that the reason for the contradictory data was caused by the mislabeling of the background strain for JNK2 KO mice by the vendor [137], which led to the use of WT and KO mice with mismatched genetic background