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Production of haemoglobin is dependent on Vitamin B12, which cannot be made in the body and, therefore, must be obtained from the diet
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There is evidence for three potentially related pathophysiological processes consistent with the characteristic time course of illness
After Opening: For multi-dose vials of B12 injections, there is always a specific shelf life after the vial has been opened
A method for preventing drug-induced ototoxicity in an individual in need thereof comprising intratympanic administration of a pharmaceutical composition comprising a therapeutic agent, wherein the therapeutic agent is an antioxidant or anti-apoptotic agent, wherein the pharmaceutical composition is administered prior to onset of therapy with the drug, and wherein the composition provides sustained release of the therapeutic agent into the ear for a period of at least 5 days after a single administration
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