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These are complementary approaches one increases supply, the other reduces waste

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More broadly, this cautions against viewing antioxidant pathway activation as uniformly protective, as excessive reductive adaptation may itself create context-specific vulnerabilities

We seek with our research a better understanding of the biology of these metabolic pathways in RA to better characterize a new approach in its therapeutic armamentarium

In pursuit of alleviating cell damage caused by glutamate-induced excitotoxicity, current drug research mainly focuses on NMDAR antagonists