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they create what researchers refer to as a massive immunological "energy sink." Because the immune cells (particularly T-cells and memory lymphocytes) are trapped in a state of severe oxidative stress, they are forced to consume excessive amounts of the host's energy just to survive the ongoing cellular damage and attempt repairs

pylori have higher levels of IL-18 and IFN-, IFN- promotes the cellular synthesis of IL-18, by boosting the production of caspase-3, the intracellular cysteine protease ICE (caspase-1) contributes to the processing of IL-18s active form and to the induction of apoptosis in gastric epithelial cells (Shimada et al., 2008

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doi: 10.1016/j.neuro.2023.03.004 70 HanX.LiQ.LanX.el-MuftiL.RenH.WangJ

The role of copper in tau-related pathology in Alzheimers disease