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It also appears to support angiogenesis and counteract the negative effects of corticosteroids on healing. However, despite over two decades of preclinical research, there is a paucity of clinical trials evaluating its use for musculoskeletal injuries in humans, and it remains unapproved for medical use by regulatory bodies. Collagen peptides do have human clinical data

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome