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Here, some info to know: Berberine works by activating an enzyme called AMPK (activated protein kinase), which helps manage metabolism, according to lab and animal studies

In Wang et al., there were still a high number of differences, namely, 12,159 DMPs (related to embryonic skeletal system development, MAPK activity activation, response to hormone stimulus, regulation of cell adhesion, and apoptosis) and 6142 DMRs [61]

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