A phytochemical constituent, (E)-methyl-cinnamate isolated from Alpinia katsumadai Hayata suppresses cell survival, migration, and differentiation in pre-osteoblasts
As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients
Cognitive Enhancement Studies Cognitive improvement studies in 28-month-old mice (equivalent to elderly humans) using 10 mg/kg body weight administered 5x per week for 3 weeks demonstrated: Significantly faster escape hole finding in Box Maze tests (trials 4 and 5) Evidence of decreased brain inflammation Increased histone deacetylase 2 labeling indicating epigenetic pathway activation Preliminary reversal of age-related cognitive impairment Pain and Anxiety Modulation Anti-pain effects in mice at 0.5 mg/kg showed efficacy comparable to cimetidines human analgesic effects, affecting 7 anti-pain genes (increased) and 2 genes (decreased), with upregulated opioid receptors and related pain-modulating pathways
Foods like leafy greens, fatty fish, and berries are excellent choices
155 The multi-nutrient tablet provided: In an uncontrolled clinical trial that included 31 participants with one-sided tinnitus, 18 weeks of treatment with a multi-nutrient supplement, providing glycerophosphorylcholine (55 mg/day), glycerophosphorylethanolamine (45 mg/day), beta-carotene (6,000 mcg RAE/day), vitamin C (180 mg/day), and vitamin E (10 mg/day), led to reductions in tinnitus loudness and discomfort